Publications

2025

Manuela Costa, Daniel Pacheco-Estefan, Antonio Gil-Nagel, Rafael Toledano, Lukas Imbach, Johannes Sarnthein, Bryan A Strange (2025)
Human hippocampal reactivation of amygdala encoding-related gamma patterns during aversive memory retrieval. Nature Communications, 1-10

Bryan Strange, Qumars Behfar, Marta Garo-Pascual, Linda Zhang, Hannes Gramespacher, Miguel Medina, Gereon Fink, Teodoro del Ser, Oezguer Onur (2025)
Superagers resist an age-related anteroposterior shift in intrinsic connectivity. Publication date – 2025/7/11

Andrés Pérez-Segura, Jorge Medina, Antonio Cerdán Cerdá, Cristina Sánchez-Ferri, Daniel Torres, Claudio R Mirasso, Bryan Strange, Víctor M Eguíluz, Lucas Lacasa, Santiago Canals (2025)
NAc-DBS selectively enhances memory updating without effect on retrieval. Neuropsychopharmacology, 1-10

Clàudia Olivé, Itziar de Rojas, Linda Zhang, Oscar Sotolongo-Grau, Inés Quintela, Pablo García-González, Raquel Puerta, Fernando García-Gutiérrez, Laura Montrreal, Maria Capdevila-Bayo, Andrea Miguel, Josep Blazquez-Folch, Miguel Calero, Alberto Rábano, Ana Belén Pastor, Teodoro del Ser, Miguel Medina, Ángel Carracedo, Alfredo Ramírez, Laura Molina-Porcel, Lluís Tàrraga, Amanda Cano, Sergi Valero, Marta Marquié, Pascual Sánchez-Juan, Mercè Boada, Bryan Strange, Maria Victoria Fernández, Agustín Ruiz (2025)
Genetic dissection of hippocampal sclerosis of ageing using magnetic resonance imaging surrogates. medRxiv, 2025.03. 10.25323307

Haeun Sun, Ningfei Li, Alejandro Granados Martinez, Fahmida A Chowdhury, Beate Diehl, Harith Akram, Veerle Visser-Vandewalle, Bryan Strange, Juan A Barcia, Mircea Polosan, Stéphan Chabardes, Davide Giampiccolo, Vladimir Litvak (2025)
Intracranial Stimulation in Epilepsy as a Novel Approach for Mapping Psychiatric Circuits medRxiv, 2025.06. 28.25330302

2024

Linda Zhang, Eva Alfayate, Miguel Calero, Miguel Medina, Michel J Grothe, Pascual Sanchez‐Juan, Bryan A Strange (2024)
KLOTHO‐VS heterozygosity ameliorates the effects of APOE ε4 on longitudinal hippocampal atrophy. Alzheimer’s & Dementia 20, e093899

L Zhang, J Silva Rodríguez, E Alfayate Sáez, M Calero Lara, M Medina, P Sánchez Juan, B Strange, M Grothe (2024)
21527. LA HETEROCIGOSIDAD KLOTHO-VS MITIGA LOS EFECTOS DE APOE-ɛ4 EN LA ATROFIA DEL HIPOCAMPO. Neurology Perspectives 4, 277

Rachele Robbio, Marta Suárez-Pinilla, Dunja Duran, Darya Frank, Nicola Moccaldi, Elisa Visani, Ryan M Hill, Holly Schofield, Matthew Brookes, Robin Hellerstedt, Pasquale Arpaia, Marco De Curtis, Paola Lanteri, Bryan Strange, Giulia Varotto (2024)
Validation of Non-Invasive MEG Techniques for Detecting Hippocampal and Visual Cortex Responses to Entropy and Surprise. IEEE International Conference on Metrology for eXtended 283-288

M Suárez-Pinilla, H Schofield, R Hill, M Brookes, C Mathys, B Strange (2024)
Hippocampal processing of levels of uncertainty and environmental volatility. OPM-MEG correlates of learning through levels of uncertainty by a hierarchical Gaussian filter. IEEE International Conference on Metrology for eXtended Reality, Artificial Intelligence and Neural Engineering (MetroXRAINE) 260-265

Víctor M Serrano del Pueblo, Gemma Serrano-Heras, Carlos M Romero Sánchez, Pepa Piqueras Landete, Laura Rojas-Bartolome, Inmaculada Feria, Richard GM Morris, Bryan Strange, Francisco Mansilla, Linda Zhang, Beatriz Castro-Robles, Lourdes Arias-Salazar, Susana López-López, María Payá, Tomás Segura, Mónica Muñoz-López (2024)
Brain and cognitive changes in patients with long COVID compared with infection-recovered control subjects. Brain 147 (10), 3611-3623

Garance M Meyer, Barbara Hollunder, Ningfei Li, Konstantin Butenko, Till A Dembek, Lauren Hart, Cristina Nombela, Philip Mosley, Harith Akram, Nicola Acevedo, Benjamin M Borron, Tina Chou, Juan Pablo Castaño Montoya, Bryan Strange, Juan A Barcia, Himanshu Tyagi, David J Castle, Andrew H Smith, Ki Sueng Choi, Brian H Kopell, Helen S Mayberg, Sameer A Sheth, Wayne K Goodman, Albert FG Leentjens, R Mark Richardson, Susan L Rossell, Peter Bosanac, G Rees Cosgrove, Jens Kuhn, Veerle Visser-Vandewalle, Martijn Figee, Darin D Dougherty, Shan H Siddiqi, Ludvic Zrinzo, Eileen Joyce, Juan Carlos Baldermann, Michael D Fox, Clemens Neudorfer, Andreas Horn (2024) Deep brain stimulation for obsessive-compulsive disorder: Optimal stimulation sites. Biological psychiatry 96 (2), 101-113

Dustin Fetterhoff, Manuela Costa, Robin Hellerstedt, Rebecca Johannessen, Lukas Imbach, Johannes Sarnthein, Bryan A Strange (2024) Neuronal population representation of human emotional memory. Cell Reports 43 (4)

D Ortega‐Cruz, KS Bress, H Gazula, A Rabano, JE Iglesias, BA Strange (2024) Three‐dimensional histology reveals dissociable human hippocampal long‐axis gradients of Alzheimer’s pathology. Alzheimer’s & Dementia 20 (4), 2606-2619

Elaheh Moradi, Mithilesh Prakash, Anette Hall, Alina Solomon, Bryan Strange, Jussi Tohka, Alzheimer’s Disease Neuroimaging Initiative (2024) Machine learning prediction of future amyloid beta positivity in amyloid-negative individuals. Alzheimer’s Research & Therapy 16 (1), 46

Manuela Costa, Daniel Pacheco, Antonio Gil-Nagel, Rafael Toledano, Lukas Imbach, Johannes Sarnthein, Bryan A Strange (2024) Retrieval of human aversive memories involves reactivation of gamma activity patterns in the hippocampus that originate in the amygdala during encoding. bioRxiv, 2024.01. 18.576178

Beatriz Sánchez‐Moreno, Linda Zhang, Gloria Mateo, Fernando Moldenhauer, Mikael Brudfors, John Ashburner, Parashkev Nachev, Diego Real De Asúa, Bryan A Strange (2024) Voxel‐based dysconnectomic brain morphometry with computed tomography in Down syndrome. Annals of Clinical and Translational Neurology 11 (1), 143-155

2023

MG Pascual, L Zhang, M Calero, M Medina, J Defelipe, BA Strange (2023) Telomere length in the superager sample of the Vallecas Project cohort. Alzheimer’s & Dementia 19, e076263

Ashwani Jha, Beate Diehl, Bryan Strange, Anna Miserocchi, Fahmida Chowdhury, Andrew W McEvoy, Parashkev Nachev (2023) 23 How the emotions of others capture our attention: a human amygdala disruption study. Journal of Neurology, Neurosurgery & Psychiatry 94 (12), e2

D Ortega‐Cruz, KS Bress, H Gazula, A Rabano, JE Iglesias, BA Strange (2023) 3D Reconstruction of human brain post‐mortem photography and integration of dementia histopathology. Alzheimer’s & Dementia 19, e072234

Clàudia Olivé, Itziar de Rojas, Linda Zhang, Oscar Sotolongo‐Grau, Inés Quintela, Pablo García‐González, Ainhoa García‐Sánchez, Raquel Puerta, Sergi Valero Sr, Amanda Cano, Miguel Calero, Alberto Rabano, Ana Belén Pastor, Teodoro Ser, Miguel Medina, Pascual Sanchez‐Juan, Bryan A Strange, Angel Carracedo, Marta Marquié, Lluís Tárraga, Mercè Boada, Agustin Ruiz (2023) Genetic dissection of Hippocampal sclerosis MRI surrogates. Alzheimer’s & Dementia 19, e074598

Sebastiaan R Ram, Bryan A Strange, Linda Zhang, Teodoro Ser, Elizabeth Lucia Valeriano Lorenzo, Meritxell Valentí, María Ascensión Zea‐Sevilla, Belén Frades, Tom Heskes, Pedro Larrañaga, Concha Bielza, Pascual Sanchez‐Juan (2023) Structural modeling of clinical factors for simultaneous validation and prediction of future conversion to mild cognitive impairment. Alzheimer’s & Dementia 19, e078737

Svenja Treu, Juan A Barcia, Cristina Torres, Anne Bierbrauer, Javier J Gonzalez-Rosa, Cristina Nombela, Jose A Pineda-Pardo, Daniel Torres, Lukas Kunz, Robin Hellerstedt, Josue M Avecillas-Chasin, Monica Lara, Marta Navas, Ana Galarza Vallejo, Julia García-Albea, Antonio Oliviero, Fernando Seijo, Andreas Horn, Ningfei Li, Nikolai Axmacher, Santiago Canals, Blanca Reneses, Bryan A Strange (2023) Deep-brain stimulation of the human nucleus accumbens-medial septum enhances memory formation. Research Square, rs. 3. rs-3476665

Giulia Varotto, Alba Peris-Yague, Manuela Costa, Antonio Gil-Nagel, Rafael Toledano, Stephan Moratti, Bryan Strange (2023) AMYGDALA-FUSIFORM CROSS-FREQUENCY COUPLING FOR PROCESSING FACES AND EMOTIONAL EXPRESSION. IBRO Neuroscience Reports 15, S906

Darya Frank, Stephan Moratti, Johannes Sarnthein, Ningfei Li, Andreas Horn, Lukas Imbach, Lennart Stieglitz, Antonio Gil-Nagel, Rafael Toledano, Karl J Friston, Bryan A Strange (2023) Human hippocampal ripples tune cortical responses in uncertain visual contexts. Cold Spring Harbor Laboratory

Marta Garo-Pascual, Christian Gaser,, Linda Zhang, Jussi Tohka, Miguel Medina, Bryan A. Strange (2023) Brain structure and phenotypic profile of superagers compared with age-matched older adults: a longitudinal analysis from the Vallecas Project. The Lancet Healthy Longevity.

Diana Ortega-Cruz*, Alicia Uceda-Heras*, Juan Eugenio Iglesias, Maria Ascension Zea-Sevilla, Bryan A Strange+, Alberto Rabano+ (2023) A novel histological staging of hippocampal sclerosis that is evident in grey matter loss in vivo. Alzheimer’s & Dementia 1-13.

2022

Bryan A Strange (2022) Hippocampus: Connecting to the long axis. Elife 11, e83718

Manuela Costa, Diego Lozano-Soldevilla, Antonio Gil-Nagel Rein, Rafael Toledano, Carina Oehrn, Lukas Kunz, Mar Yebra, Constantino Mendez-Bertolo, Lennart Stieglitz, Johannes Sarnthein, Nikolai Axmacher, Stephan Moratti, Bryan A Strange (2021) Aversive memory formation in humans involves an amygdala-hippocampus phase code.   Nature Communications 13 (1), 1-16


Svenja Treu, Juan A Barcia, Cristina Torres, Anne Bierbrauer, Javier J. Gonzalez-Rosa, Cristina Nombela, Jose A Pineda-Pardo, Daniel Torres, Lukas Kunz, Josue M Avecillas-Chasin, Monica Lara, Marta Navas, Ana Galarza Vallejo, Julia García-Albea, Antonio Oliviero, Fernando Seijo, Andreas Horn, Ningfei Li, Nikolai Axmacher, Santiago Canals, Blanca Reneses, Bryan A Strange (2022) Deep-brain stimulation of the human nucleus accumbens-medial septum enhances memory formation. Submitted.

Vanesa Soto-León, Mabel Torres-Llacsa, Laura Mordillo-Mateos, Carmen Carrasco-López, José A Pineda-Pardo, Ana I Velasco, Laura Abad-Toribio, Jesús Tornero, Guglielmo Foffani, Bryan A Strange, Antonio Oliviero (2022) Static magnetic field stimulation over motor cortex modulates resting functional connectivity in humans. Scientific Reports, 12 (1), 1-10.

Ashwani Jha, Beate Diehl, Bryan Strange, Anna Miserocchi, Fahmida Chowdhury, Andrew W McEvoy, Parashkev Nachev (2022) Orienting to fear under transient focal disruption of the human amygdala. Brain (In press).

Darya Frank, Marta Garo-Pascual, Pablo Alejandro Reyes Velasquez, Belen Frades, Noam Peled, Linda Zhang, Bryan Strange (2022). A hippocampal-anterior thalamic circuit associated with learning rate in ageing, NeuroImage
263, 119630

Juan A Barcia, María Aurora Viloria, Raquel Yubero, Leyre Sanchez-Sanchez-Rojas, Amanda López, Bryan Andrew Strange, María Cabrera, Leonides Canuet, Pedro Gil, Cristina Nombela (2022) Directional DBS of the Fornix in Alzheimer’s Disease Achieves Long-Term Benefits: A Case Report. Frontiers in Aging Neuroscience, 14. doi: 10.3389/fnagi.2022.809972

2021

Ningfei Li, Barbara Hollunder, Juan Carlos Baldermann, Astrid Kibleur, Svenja Treu, Harith Akram, Bassam Al-Fatly, Bryan A Strange, Juan A Barcia, Ludvic Zrinzo, Eileen M Joyce, Stephan Chabardes, Veerle Visser-Vandewalle, Mircea Polosan, Jens Kuhn, Andrea A Kühn, Andreas Horn (2021) A unified functional network target for deep brain stimulation in obsessive-compulsive disorder Biological Psychiatry, 90(10) 701-713.

Cristina V Torres Díaz, Svenja Treu, Bryan Strange, Monica Lara, Marta Navas, Elena Ezquiaga, Elisa Seijo Zazo, Juncal Sevilla Vicente, Isabel Muñiz, Fernando Seijo Fernandez (2021) Deep Brain Stimulation of the Nucleus Accumbens, Ventral Striatum, or Internal Capsule Targets for Medication-Resistant Obsessive-Compulsive Disorder: A Multicenter Study. World Neurosurgery (155) 168-176.

M Yebra, O Jensen, L Kunz, S Moratti, N Axmacher, BA Strange (2021) A gradient of electrophysiological novelty responses along the human hippocampal long axis. [bioRXiv]

Bryan Strange, Linda Zhang, Alba Sierra-Marcos, Eva Alfayate, Jussi Tohka, Miguel Medina (2021) Predicting the future development of mild cognitive impairment in the cognitively healthy elderly [bioRXiv]

Svenja Treu, Javier J. Gonzalez-Rosa, Vanesa Soto-Leon, Diego Lozano-Soldevilla, Antonio Oliviero, Fernando Lopez-Sosa, Blanca Reneses-Prieto, Juan A Barcia, Bryan A Strange (2021) A ventromedial prefrontal dysrhythmia in obsessive-compulsive disorder is attenuated by nucleus accumbens deep brain stimulation. Brain Stimulation 14(4) 761-770.

N Li , B Hollunder, JC Baldermann, A Kibleur, S Treu, H Akram, B Al-Fatly, B Strange, JA. Barcia, L Zrinzo, E Joyce, S Chabardes, V Visser-Vandewalle, M Polosan, J Kuhn, AA. Kühn, A Horn (2021) A unified functional network target for deep brain stimulation in obsessive-compulsive disorder. Biological Psychiatry. In press.

Lopez-Sosa F, Reneses B, Sanmartino F, Galarza-Vallejo A, Garcia-Albea J, Cruz-Gomez AJ, Yebra M, Oliviero A, Barcia JA, Strange BA, Gonzalez-Rosa JJ (2021) Nucleus Accumbens Stimulation modulates inhibitory control by right prefrontal cortex activation in obsessive-compulsive disorder. Cerebral Cortex 31:2742-2758.

M Prakash, M Abdelaziz, L Zhang, BA Strange, J Tohka (2021) Quantitative longitudinal predictions of Alzheimer’s disease by multi-modal predictive learning. Journal of Alzheimer’s Disease 79:1533-1546

2020

Anne Bierbrauer, Lukas Kunz, Carlos A Gomes, Maike Luhmann, Lorena Deuker, Stephan Getzmann, Edmund Wascher, Patrick D Gajewski, Jan G Hengstler, Marina Fernandez-Alvarez, Mercedes Atienza, Davide M Cammisuli, Francesco Bonatti, Carlo Pruneti, Antonio Percesepe, Youssef Bellaali, Bernard Hanseeuw, Bryan A Strange, Jose L Cantero, Nikolai Axmacher (2020) Unmasking selective path integration deficits in Alzheimer’s disease risk carriers. Science Advances 6(35):eaba1394 .

Svenja Treu, Bryan Strange, Simon Oxenford, Andrea Kühn, Ningfei Li, Andreas Horn (2020) Deep Brain Stimulation: Imaging on a group level. NeuroImage 219:117018

Ningfei Li, Juan Carlos Baldermann, Astrid Kibleur, Svenja Treu, Harith Akram, Gavin J B Elias, Alexandre Boutet, Andres M Lozano, Bassam Al-Fatly, Bryan Strange, Juan Barcia, Ludvic Zrinzo, Eileen Joyce, Stephan Chabardes, Veerle Visser-Vandewalle, Mircea Polosan, Jens Kuhn, Andrea A Kühn, and Andreas Horn (2020) A unified connectomic target for deep brain stimulation in obsessive-compulsive disorder.  Nature Communications 11:3364

Raphael Guex, Constantino Méndez-Bértolo, Stephan Moratti, Bryan A. Strange, Laurent Spinelli, Ryan J. Murray, David Sander, Margitta Seeck, Patrik Vuilleumier & Judith Domínguez-Borràs (2020) Temporal dynamics of amygdala response to emotion- and action-relevance. Scientific Reports 10:11138

Adam Fijtman,Joana Bücker, Bryan A Strange, Dayane Santos Martins, Ives Passos, Mathias Hasse-Sousa, Flávia Moreira Lima, Flávio Kapczinski, Lakshmi Yatham, Marcia Kauer-Sant’Anna (2020) Emotional Memory in Bipolar Disorder: Impact of Multiple Episodes and Childhood Trauma. Journal of Affective Disorders 260:206-213.


2019

Ana Galarza Vallejo, Marijn CW Kroes, Enrique Rey, Maria Victoria Acedo, Stephan Moratti, Guillén Fernández, Bryan A. Strange (2019) Propofol-induced deep sedation reduces emotional episodic memory reconsolidation in humans. Science Advances 5(3):eaav3801.

Mar Yebra, Ana Galarza Vallejo, Vanesa Soto-Leon, Javier J  Gonzalez-Rosa, Archy O de Berker, Sven Bestmann, Antonio Oliviero, Marijn CW Kroes, Bryan A Strange (2019) Action boosts episodic memory encoding in humans via engagement of a noradrenergic system. Nature Communications 10(1):3534.

José A. Pineda-Pardo, I. Obeso, Pasqualina Guida, Michele Dileone, Bryan A. Strange, José A. Obeso, Antonio Oliviero, Guglielmo Foffani (2019) Transcranial static magnetic field stimulation of the supplementary motor area modulates local resting-state activity, distant functional connectivity and motor behavior. Communications Biololgy 2:397.

Judith Domínguez-Borràs, Raphaël Guex, Constantino Méndez-Bértolo, Guillaume Legendre, Laurent Spinelli, Stephan Moratti, Sascha Frühholz, Pierre Mégevand, Luc Arnal, Bryan Strange, Margitta Seeck, Patrik Vuilleumier (2019) Human amygdala response to unisensory and multisensory emotion input: No evidence for superadditivity from intracranial recordings. Neuropsychologia 131:9-24.

JA Barcia, J Avecillas, C Nombela, R Arza, J García-Albea, J-A Pineda, B Reneses, BA Strange (2019) Personalized striatal targets for deep-brain stimulation in obsessive-compulsive disorder. Brain Stimulation 12:724-734.


2018

Lozano-Soto E, Soto-León V, Sabbarese S, Ruiz-Alvarez L, Sanchez-Del-Rio M, Aguilar J, Strange BA, Foffani G, Oliviero A (2018) Transcranial static magnetic field stimulation (tSMS) of the visual cortex decreases experimental photophobia. Cephalalgia Jan 1:333102417736899.


2017

Carrasco-López C, Soto-León V, Céspedes V, Profice P, Strange BA, Foffani G, Oliviero A (2017) Static Magnetic Field Stimulation over Parietal Cortex Enhances Somatosensory Detection in Humans. Journal of Neuroscience 37:3840-3847.


2016

Méndez-Bértolo C, Moratti S, Toledano R, Lopez-Sosa F, Martínez-Alvarez R, Mah YH, Vuilleumier P, Gil-Nagel A, Strange BA (2016) A fast pathway for fear in human amygdala. Nature Neuroscience 19:1041-9.

— features in Research Highlights in Nature Reviews Neuroscience Emotion: Fast Fear

Strange BA, Galarza A (2016) Bidirectional synaptic plasticity can explain bidirectional retrograde effects of emotion on memory. Behavioral and Brain Science 39:e224


2015

Nachev P, Lopez-Sosa F, Gonzalez-Rosa JJ, Galarza A, Avecillas J, Pineda-Pardo JA, Lopez-Ibor JJ, Reneses B, Barcia JA,  Strange BA (2015) Dynamic risk control by human nucleus accumbens. Brain 38:3496-3502.

Gonzalez-Rosa JJ, Soto-León V, Real P, Carrasco-López MC, Foffani G, Strange BA, Oliviero A (2015) Static magnetic field stimulation over the visual cortex increases alpha oscillations and slows visual search in humans. Journal of Neuroscience 35:9182-9193.

Avila J, Perry G, Strange BA, Hernandez F (2015) Alternative neural circuitry that might be impaired in the development of Alzheimer disease. Frontiers in Neuroscience 9:145.

Strange BA, Yebra M (2015) The multi-instrumentalist hippocampus: Comment on “The quartet theory of human emotions: An integrative and neurofunctional model” by S. Koelsch et al. Physics of Life Reviews 13:85-6.

Moratti S, Strange B, Rubio G (2015) Emotional arousal modulation of right temporoparietal cortex in depression depends on parental depression status in women: First evidence. Journal of Affective Disorders 178:79-87.


2014

Strange BA, Witter MP, Lein ES, Moser EI (2014) Functional organization of the hippocampal longitudinal axis. Nature Reviews Neuroscience 15:655-69. pubmed

Kroes MCW, Tendolkar I, van Wingen G , van Waarde J , Strange BA, Fernandez G (2014) An electroconvulsive therapy procedure impairs reconsolidation of episodic memories in humans. Nature Neuroscience 17:204–206 pubmed

Oliviero A, Carrasco-López MC, Campolo M, Perez-Borrego YA, Soto-León V, Gonzalez-Rosa JJ, Higuero AM, Strange BA, Abad-Rodriguez J, Foffani G (2014) Safety Study of Transcranial Static Magnetic Field Stimulation (tSMS) of the Human Cortex. Brain Stimulation 8:481-5.

Moratti S, Méndez-Bértolo C, del-Pozo F, Strange BA (2014) Dynamic gamma frequency feedback coupling between higher and lower order visual cortex underlies perceptual completion in humans. Neuroimage 86:470-479 pubmed

Strange BA, Gartmann N, Brenninkmeyer J, Haaker J, Reif A, Kalisch R, Büchel C (2014) Dopamine receptor 4 promoter polymorphism modulates memory and neuronal responses to salience. Neuroimage 84:922–931 pubmed


2013

Toledano R, Jiménez-Huete A, García-Morales I, Campo P, Poch C, Strange BA, Gil-Nagel A (2013) Aphasic seizures in patients with temporopolar and anterior temporobasal lesions: A video-EEG study. Epilepsy & Behavior 29:172-177. pubmed


2012

Gupta S, Fiertag O, Thanulingam T, Ros E, Strange BA, Warner J (2012) Further rare and unusual dementias. Advances in Psychiatric Treatment 18:67-77.


2011

Moratti S, Saugar C, Strange BA (2011) Prefrontal-occipitoparietal coupling underlies late latency human neuronal responses to emotion. Journal of Neuroscience 31:17278-86. pubmed